4-Bromobenzyl bromide → HCID 11531150, compound

Participants

Reaction Steps

Following general procedure B2 and D1, 3-(2,4-dimethoxy-benzyloxy)-1H-benzo[4,5]furo[3,2-d]pyrimidine-2,4-dione was alkylated with 4-bromobenzyl bromide and subsequently deprotected to provide the title compound as a white solid. 1H NMR (d6-DMSO, 300 MHz) δ 5.52 (s, 2H); 7.29-7.40 (m, 3H); 7.52 (d, J=8 Hz, 2H); 7.60 (dd, J=8 Hz, 1H); 7.75-7.81 (m, 2H); Ret. time=2.70 min., m/z=387.0.

Provenance & Evidence