HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobutyramide → 2-Amino-6-aminomethylcarbonylamino-4-[2-(3-aminocarbonylpropoxy)phenyl]quinazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobutyramide | HCID 75564 | — |
| Reactant | 2-Amino-6-aminomethylcarbonylamino-4-(2-hydroxyphenyl)quinazoline | HCID 136284754 | — |
| Product | 2-Amino-6-aminomethylcarbonylamino-4-[2-(3-aminocarbonylpropoxy)phenyl]quinazoline | HCID 15948458 | — |
Reaction Steps
Analogous reaction of 2-amino-6-aminomethylcarbonylamino-4-(2-hydroxyphenyl)quinazoline with 4-chlorobutyramide gives the compound 2-amino-6-aminomethylcarbonylamino-4-[2-(3-aminocarbonylpropoxy)phenyl]quinazoline (“A61”).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07947696B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-e1db0196b8d44a4b9090ce38108986b8 |
| Source note | uspto-grants-2011_05 |