Hydrochloric Acid → HCID 136355283, compound

Participants

Reaction Steps

To a mixture of tert-butyl 2-(4-chloro-2,5-difluorophenyl)-4-oxo-3,5,6,7-tetrahydro-4H-pyrrolo[3,4-d]pyrimidine-6-carboxylate, chloroform, and MeOH, 4M hydrogen chloride (HCl) in ethyl acetate (EtOAc) solution was added, and the resultant mixture was stirred at ambient temperature for 5 hours to yield 2-(4-chloro-2,5-difluorophenyl)-3,5,6,7-tetrahydro-4H-pyrrolo[3,4-d]pyrimidin-4-one hydrochloride.

Provenance & Evidence