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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 550783Generated: October 30, 2026

Phosphorus oxychloride → HCID 59686245, compound

https://huagongshe.com/reaction/550783

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxychlorideHCID 24813—
ReactantHCID 178517533HCID 178517533—
ProductHCID 59686245HCID 59686245—

Reaction Conditions

Temperature90 °C

Reaction Steps

A mixture of 2-(4-chloro-2,5-difluorophenyl)-5,7-dihydrothieno[3,4-d]pyrimidin-4(1H)-one and phosphorous oxychloride was stirred at 90° C. for 4 hours to yield 4-chloro-2-(4-chloro-2,5-difluorophenyl)-5,7-dihydrothieno[3,4-d]pyrimidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947690B2
Source datasetuspto-grants-2011_05
ORD IDord-a8c55af0a48c47b18aa9d78e4aded153
Source noteuspto-grants-2011_05