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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 550922Generated: October 31, 2026

2-Isocyanato-1,4-dimethoxybenzene → 3-{4-[3-(2,5-dimethoxyphenyl)ureido]phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamide

https://huagongshe.com/reaction/550922

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Isocyanato-1,4-dimethoxybenzeneHCID 4178425—
Reactant3-(4-aminophenyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamideHCID 57445354—
Product3-{4-[3-(2,5-dimethoxyphenyl)ureido]phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamideHCID 57445314—

Reaction Steps

33.1 mg of yellow lyophilizate 3-{4-[3-(2,5-dimethoxyphenyl)ureido]phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamide are prepared as described in Example 7 starting with 3-(4-aminophenyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide and 2,5-dimethoxyphenyl isocyanate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947706B2
Source datasetuspto-grants-2011_05
ORD IDord-efb76eb2e8024c1c98f271e6807bdae2
Source noteuspto-grants-2011_05