HCID 86629741, compound → HCID 86629742, compound

Participants

Reaction Steps

A solution of (±)-ethyl (4-amino-6-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl)acetate from Step D (3.28 g, 13.0 mmol) in degassed xylenes (100 mL) and AcOH (5 mL) was heated at reflux for 4.5 days, then allowed to slowly cool to ambient temperature. The resulting precipitate was filtered, washing with hexanes, to give the title compound. MS: m/z=207 (M+1).

Provenance & Evidence