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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 551215Generated: November 1, 2026

Trifluoroacetic acid → (S)-1-(5-chloro-1H-benzimidazol-2-yl)-3-methoxypropylamine

https://huagongshe.com/reaction/551215

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 178495124HCID 178495124—
SolventDichloromethaneHCID 6344—
Product(S)-1-(5-chloro-1H-benzimidazol-2-yl)-3-methoxypropylamineHCID 178495121—

Reaction Steps

Prepared analogously to Example 1g from (1S)—N-Boc-1-(5-chloro-1H-benzimidazol-2-yl)-3-methoxy-propylamine and TFA in dichloromethane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947700B2
Source datasetuspto-grants-2011_05
ORD IDord-ba94615ce5184108849f489c1dfb3f74
Source noteuspto-grants-2011_05