HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 178427144, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| Reactant | (S)-1-(5-chloro-1H-benzimidazol-2-yl)ethylamine | HCID 42034613 | — |
| Reactant | 4-(4,4-Dimethyl-2-oxo-imidazolidin-1-yl)-3-methyl-benzoic acid | HCID 66731535 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178427144 | HCID 178427144 | — |
Reaction Steps
Prepared analogously to Example 1f from 4-(4,4-dimethyl-2-oxo-imidazolidin-1-yl)-3-methyl-benzoic acid, (1S)-1-(5-chloro-1H-benzimidazol-2-yl)-ethylamine, TBTU and DIPEA in THF and purification of the residue by chromatography on silica gel.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07947700B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-a87f2053c8a04e978b138e90372dcc3b |
| Source note | uspto-grants-2011_05 |