Benzoic Acid → HCID 45268485, compound

HRID 551462Notes

Reaction equation

HRID 551462 reaction equation
[C:1]([OH:9])(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:10]([NH:12][CH2:13][C:14]([CH2:20][NH:21][C:22]1[CH:30]=[C:29]([CH3:31])[CH:28]=[C:27]2[C:23]=1[CH:24]=[N:25][N:26]2[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1)([OH:19])[C:15]([F:18])([F:17])[F:16])[CH3:11]>>[CH2:10]([N:12]([CH2:13][C:14]([OH:19])([CH2:20][NH:21][C:22]1[CH:30]=[C:29]([CH3:31])[CH:28]=[C:27]2[C:23]=1[CH:24]=[N:25][N:26]2[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1)[C:15]([F:18])([F:17])[F:16])[C:1](=[O:9])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)[CH3:11]

Participants

3

Reactant 2

HCID 243Benzoic AcidHCID 593241363-(Ethylamino)-1,1,1-trifluoro-2-{[(6-methyl-1-phenyl-1H-indazol-4-yl)amino]methyl}-2-propanol

Product 1

HCID 45268485HCID 45268485, compound

Procedure

Prepared similarly to Example 11 from benzoic acid and 3-(ethylamino)-1,1,1-trifluoro-2-{[(6-methyl-1-phenyl-1H-indazol-4-yl)amino]methyl}-2-propanol.

Sources & evidence

ORD record
ord-3a9620815a3a428f8ee4d1dbc9f2fe59
Source dataset
uspto-grants-2011_05
Patent number
US07947727B2

Reaction notes

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