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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 551464Generated: October 31, 2026

2-Thiophenecarboxylic acid → N-Ethyl-N-(3,3,3-trifluoro-2-hydroxy-2-{[(1-phenyl-1H-indazol-4-yl)amino]methyl}propyl)-2-thiophenecarboxamide

https://huagongshe.com/reaction/551464

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiophenecarboxylic acidHCID 10700—
Reactant3-(Ethylamino)-1,1,1-trifluoro-2-{[(1-phenyl-1H-indazol-4-yl)amino]methyl}-2-propanolHCID 59324157—
ProductN-Ethyl-N-(3,3,3-trifluoro-2-hydroxy-2-{[(1-phenyl-1H-indazol-4-yl)amino]methyl}propyl)-2-thiophenecarboxamideHCID 59324144—

Reaction Steps

Prepared similarly to Example 1 from 2-thiophenecarboxylic acid and 3-(Ethylamino)-1,1,1-trifluoro-2-{[(1-phenyl-1H-indazol-4-yl)amino]methyl}-2-propanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947727B2
Source datasetuspto-grants-2011_05
ORD IDord-63510c9689e042b7b128710c0f9b922c
Source noteuspto-grants-2011_05