Thiophene-3-carboxylic acid → HCID 59324148, compound

HRID 551470Notes

Reaction equation

HRID 551470 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]([C:6]([OH:8])=O)=[CH:2]1.[F:9][C:10]([F:36])([F:35])[C:11]([CH2:30][NH:31][CH2:32][CH2:33][CH3:34])([OH:29])[CH2:12][NH:13][C:14]1[CH:22]=[CH:21][CH:20]=[C:19]2[C:15]=1[CH:16]=[N:17][N:18]2[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[CH2:32]([N:31]([CH2:30][C:11]([OH:29])([CH2:12][NH:13][C:14]1[CH:22]=[CH:21][CH:20]=[C:19]2[C:15]=1[CH:16]=[N:17][N:18]2[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[C:10]([F:36])([F:35])[F:9])[C:6]([C:3]1[CH:4]=[CH:5][S:1][CH:2]=1)=[O:8])[CH2:33][CH3:34]

Participants

3

Reactant 2

HCID 6918Thiophene-3-carboxylic acidHCID 593241711,1,1-Trifluoro-3-[(1-phenyl-1H-indazol-4-yl)amino]-2-[(propylamino)methyl]-2-propanol

Product 1

HCID 59324148HCID 59324148, compound

Procedure

Prepared similarly to Example 1 from 3-thiophenecarboxylic acid and 1,1,1-trifluoro-3-[(1-phenyl-1H-indazol-4-yl)amino]-2-[(propylamino)methyl]-2-propanol.

Sources & evidence

ORD record
ord-8c37b5a4ec8b425c918a3a3ddba425f6
Source dataset
uspto-grants-2011_05
Patent number
US07947727B2

Reaction notes

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