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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 551480Generated: October 31, 2026

Thiophene-3-carboxylic acid → N-Propyl-N-(3,3,3-trifluoro-2-hydroxy-2-{[(6-methyl-1-phenyl-1H-indazol-4-yl)amino]methyl}propyl)-3-thiophenecarboxamide

https://huagongshe.com/reaction/551480

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThiophene-3-carboxylic acidHCID 6918—
Reactant1,1,1-Trifluoro-3-[(6-methyl-1-phenyl-1H-indazol-4-yl)amino]-2-[(propylamino)methyl]-2-propanolHCID 59324127—
ProductN-Propyl-N-(3,3,3-trifluoro-2-hydroxy-2-{[(6-methyl-1-phenyl-1H-indazol-4-yl)amino]methyl}propyl)-3-thiophenecarboxamideHCID 59324164—

Reaction Steps

Prepared similarly to Example 11 from 3-thiophenecarboxylic acid and 1,1,1-trifluoro-3-[(6-methyl-1-phenyl-1H-indazol-4-yl)amino]-2-[(propylamino)methyl]-2-propanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947727B2
Source datasetuspto-grants-2011_05
ORD IDord-1072d4112e6f4052bbad3b51183f7c4e
Source noteuspto-grants-2011_05