HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoro-6-(trifluoromethyl)benzoyl chloride → N-Ethyl-2-fluoro-N-[3,3,3-trifluoro-2-({[1-(4-fluorophenyl)-6-methyl-1H-indazol-4-yl]amino}methyl)-2-hydroxypropyl]-6-(trifluoromethyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoro-6-(trifluoromethyl)benzoyl chloride | HCID 145458 | — |
| Reactant | 3-(Ethylamino)-1,1,1-trifluoro-2-({[1-(4-fluorophenyl)-6-methyl-1H-indazol-4-yl]amino}methyl)-2-propanol | HCID 59324145 | — |
| Product | N-Ethyl-2-fluoro-N-[3,3,3-trifluoro-2-({[1-(4-fluorophenyl)-6-methyl-1H-indazol-4-yl]amino}methyl)-2-hydroxypropyl]-6-(trifluoromethyl)benzamide | HCID 59324143 | — |
Reaction Steps
Prepared similarly to Example 48 from 2-fluoro-6-(trifluoromethyl)benzoyl chloride and 3-(ethylamino)-1,1,1-trifluoro-2-({[1-(4-fluorophenyl)-6-methyl-1H-indazol-4-yl]amino}methyl)-2-propanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07947727B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-3bd00bb9d8f04397ab5d875d56bbcb01 |
| Source note | uspto-grants-2011_05 |