HuagongsheHuagongshe Chemistry Print Report · For research reference only
Di-tert-butyl dicarbonate → Tert-butyl 4-formyl-1H-indole-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Di-tert-butyl dicarbonate | HCID 90495 | — |
| Reactant | Indole-4-carboxaldehyde | HCID 333703 | — |
| Reactant | Tert-butyl 6-formyl-1H-indole-1-carboxylate | HCID 14616867 | — |
| Product | Tert-butyl 4-formyl-1H-indole-1-carboxylate | HCID 49758854 | — |
Reaction Steps
4-Formyl-indole-1-carboxylic acid tert-butyl ester was synthesized by a procedure similar to 6-Formyl-indole-1-carboxylic acid tert-butyl ester from starting materials 1H-Indole-4-carbaldehyde and di-tert-butyl-dicarbonate to yield the product as a clear yellow oil (2 g, 80%). LC-MS (ES) calculated for C14H15NO3, 245.1; found m/z 244 [M−H]−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07947728B1 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-9d3c443274c54beaae18c111fb2ba63b |
| Source note | uspto-grants-2011_05 |