戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 551511作成日：2026年10月25日

6-(4',5'-difluoro-2'-methoxy-biphenyl-4-yloxymethyl)-1H-indole → 4-(4',5'-Difluoro-2'-methoxy-biphenyl-4-yloxymethyl)-1H-indole

https://huagongshe.com/reaction/551511

反応式

関与物質

役割名称HCID仕込み量
反応物6-(4',5'-difluoro-2'-methoxy-biphenyl-4-yloxymethyl)-1H-indoleHCID 52939862—
反応物4-(4',5'-Difluoro-2'-methoxy-biphenyl-4-yloxymethyl)-indole-1-carboxylic acid tert-butyl esterHCID 67151940—
生成物4-(4',5'-Difluoro-2'-methoxy-biphenyl-4-yloxymethyl)-1H-indoleHCID 52939742—

反応手順

4-(4′,5′-Difluoro-2′-methoxy-biphenyl-4-yloxymethyl)-1H-indole was synthesized by a procedure similar to 6-(4′,5′-difluoro-2′-methoxy-biphenyl-4-yloxymethyl)-1H-indole from starting material 4-(4′,5′-difluoro-2′-methoxy-biphenyl-4-yloxymethyl)-indole-1-carboxylic acid tert-butyl ester to yield the product was a white solid (156 mg, 99%). LC-MS (ES) calculated for C22H17F2NO2, 365.1; found m/z 366 [M+H]+.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07947728B1
出典データセットuspto-grants-2011_05
ORD IDord-1334676a2f504b328401b70b7ac6772d
出典メモuspto-grants-2011_05