Hydrochloric Acid → HCID 67188583, compound

HRID 551802Notes

Reaction equation

HRID 551802 reaction equation
[CH2:1]([N:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[N:8]([C:15]([N:17]2[CH2:21][CH2:20][CH:19]([C:22]3[CH:23]=[N:24][CH:25]=[CH:26][CH:27]=3)[CH2:18]2)=[O:16])[CH2:7][CH2:6]1)[CH2:2][CH2:3][CH3:4].[ClH:28]>ClCCl.CCOCC>[ClH:28].[CH2:1]([N:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[N:8]([C:15]([N:17]2[CH2:21][CH2:20][CH:19]([C:22]3[CH:23]=[N:24][CH:25]=[CH:26][CH:27]=3)[CH2:18]2)=[O:16])[CH2:7][CH2:6]1)[CH2:2][CH2:3][CH3:4]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 24852913HCID 24852913, compound

Product 1

HCID 67188583HCID 67188583, compound

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 6344DichloromethaneSolvent

Procedure

0.032 g of 1-butyl-4-[(3-(pyridin-3-yl)pyrrolidin-1-yl)carbonyl]-1,2,3,4-tetrahydroquinoxaline, dissolved in 0.9 ml of dichloromethane, is introduced into a 10 ml round-bottomed flask. 0.45 ml of a 0.2N solution of hydrochloric acid in ether is subsequently added. Stirring is maintained for ten minutes. After evaporating, 0.030 g of 1-butyl-4-[(3-(pyridin-3-yl)pyrrolidin-1-yl)carbonyl]-1,2,3,4-tetrahydroquinoxaline hydrochloride is obtained.

Workup

  1. additionis introduced into a 10 ml round-bottomed flask
  2. temperatureis maintained for ten minutes
  3. customAfter evaporating

Sources & evidence

ORD record
ord-aa3cffcabe084afc84cdb5e6ba5f1095
Source dataset
uspto-grants-2011_05
Patent number
US07947834B2

Reaction notes

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