Hydrochloric Acid → HCID 67187053, compound

HRID 551807Notes

Reaction equation

HRID 551807 reaction equation
[C:1]([N:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[N:7]([C:14]([N:16]2[CH2:20][CH2:19][CH:18]([C:21]3[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=3)[CH2:17]2)=[O:15])[CH2:6][CH2:5]1)(=[O:3])[CH3:2].[ClH:27]>CCOCC>[ClH:27].[C:1]([N:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[N:7]([C:14]([N:16]2[CH2:20][CH2:19][CH:18]([C:21]3[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=3)[CH2:17]2)=[O:15])[CH2:6][CH2:5]1)(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 24852915HCID 24852915, compound

Product 1

HCID 67187053HCID 67187053, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

0.284 g of 1-acetyl-4-[(3-(pyridin-3-yl)pyrrolidin-1-yl)carbonyl]-1,2,3,4-tetrahydroquinoxaline, dissolved in 4.05 ml of a 0.2N solution of hydrochloric acid in ether, is introduced into a 25 ml round-bottomed flask. Stirring is maintained for ten minutes. After evaporating, 0.126 g of 1-acetyl-4-[(3-(pyridin-3-yl)pyrrolidin-1-yl)carbonyl]-1,2,3,4-tetrahydroquinoxaline hydrochloride is obtained.

Workup

  1. additionis introduced into a 25 ml round-bottomed flask
  2. temperatureis maintained for ten minutes
  3. customAfter evaporating

Sources & evidence

ORD record
ord-636b2033721d4be6bc3cd4519baec584
Source dataset
uspto-grants-2011_05
Patent number
US07947834B2

Reaction notes

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