2,4,6-Trimethylbenzyl chloride → 2-Cyano-6-(2,4,6-trimethylbenzyloxy)benzothiazole

HRID 552042Notes

Reaction equation

HRID 552042 reaction equation
[C:1]([C:3]1[S:4][C:5]2[CH:11]=[C:10]([O:12]CC3C=CC=CC=3C(F)(F)F)[CH:9]=[CH:8][C:6]=2[N:7]=1)#[N:2].[CH3:24][C:25]1[CH:30]=[C:29]([CH3:31])[C:28]([CH2:32]Cl)=[C:27]([CH3:34])[CH:26]=1>>[C:1]([C:3]1[S:4][C:5]2[CH:11]=[C:10]([O:12][CH2:32][C:28]3[C:29]([CH3:31])=[CH:30][C:25]([CH3:24])=[CH:26][C:27]=3[CH3:34])[CH:9]=[CH:8][C:6]=2[N:7]=1)#[N:2]

Participants

3

Reactant 2

HCID 741082,4,6-Trimethylbenzyl chlorideHCID 587977072-Cyano-6-(2-trifluoromethylbenzyloxy)benzothiazole

Product 1

HCID 587977312-Cyano-6-(2,4,6-trimethylbenzyloxy)benzothiazole

Procedure

This compound was synthesized in a similar way to 2-cyano-6-(2-trifluoromethylbenzyloxy)benzothiazole with α2-chloroisodurene (100 mg, 0.852 mmol). 168 mg product was obtained.

Sources & evidence

ORD record
ord-e6658cdab2fe46beb28cc70bf0f3e4cd
Source dataset
uspto-grants-2011_05
Patent number
US07951550B2

Reaction notes

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