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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 552042Generated: November 1, 2026

2,4,6-Trimethylbenzyl chloride → 2-Cyano-6-(2,4,6-trimethylbenzyloxy)benzothiazole

https://huagongshe.com/reaction/552042

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4,6-Trimethylbenzyl chlorideHCID 74108—
Reactant2-Cyano-6-(2-trifluoromethylbenzyloxy)benzothiazoleHCID 58797707—
Product2-Cyano-6-(2,4,6-trimethylbenzyloxy)benzothiazoleHCID 58797731—

Reaction Steps

This compound was synthesized in a similar way to 2-cyano-6-(2-trifluoromethylbenzyloxy)benzothiazole with α2-chloroisodurene (100 mg, 0.852 mmol). 168 mg product was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07951550B2
Source datasetuspto-grants-2011_05
ORD IDord-e6658cdab2fe46beb28cc70bf0f3e4cd
Source noteuspto-grants-2011_05