HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → Methyl 2-aminoisobutyrate hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Aminoisobutyric acid | HCID 6119 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Product | Methyl 2-aminoisobutyrate hydrochloride | HCID 13258034 | 89.2% |
Reaction Steps
This was synthesised according to Standard Procedure 1, using 2-amino-isobutyric acid (5.102 g, 48.49 mmol) with thionyl chloride (11.538 g, 96.98 mmol, 7.04 mL) and anhydrous methanol (19.6 mL). The product was isolated as a white solid (6.636 g, yield 89.2%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951787B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-4dc15b2cdeb2425d8b6f619f0f17144b |
| Source note | uspto-grants-2011_05 |