HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Ethyl 2-amino-2-methylpropanoate hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Aminoisobutyric acid | HCID 6119 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Product | Ethyl 2-amino-2-methylpropanoate hydrochloride | HCID 22343822 | 86.3% |
Reaction Steps
This was synthesised according to Standard Procedure 1, using 2-amino-isobutyric acid (5.102 g, 48.49 mmol) with thionyl chloride (11.772 g, 98.95 mmol, 7.2 mL) and anhydrous ethanol (29 mL). The product was isolated as a white solid (7.159 g, yield 86.3%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951787B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-94bd2d8a88fd4eeead367b1a1d1dc969 |
| Source note | uspto-grants-2011_05 |