HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → HCID 131728929, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Phosphorodichloridic acid, phenyl ester | HCID 13038 | — |
| Reactant | Methyl 2-aminoisobutyrate hydrochloride | HCID 13258034 | — |
| Product | HCID 131728929 | HCID 131728929 | 95.2% |
Reaction Steps
This is synthesised according to Standard procedure 4, using 2-aminoisobutyrate methyl ester hydrochloride (583.5 mg, 3.75 mmol), phenyl dichlorophosphate (791.1 mg, 3.75, 560 μL), and TEA (758.9 mg, 7.5 mmol, 1045 μL) in DCM (20 mL), to yield 1.041 g (95.2%) of crude product used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951787B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-35259695a22b469f9459ef04aea0ea36 |
| Source note | uspto-grants-2011_05 |