HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminopyrimidine-4-carbaldehyde → 2-(Methylamino)pyrimidine-4-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminopyrimidine-4-carbaldehyde | HCID 17832346 | — |
| Reactant | 4-(Dimethoxymethyl)-N-methylpyrimidin-2-amine | HCID 17840014 | — |
| Product | 2-(Methylamino)pyrimidine-4-carbaldehyde | HCID 22002531 | 30% |
Reaction Steps
2-Methylaminopyrimidine-4-carboxaldehyde (I-11) was synthesized in a similar manner to 2-aminopyrimidine-4-carboxaldehyde (I-9, procedure I). Reaction of crude 2-methylaminopyrimidine-4-carboxaldehyde dimethyl acetal (I-10) from procedure J provided 1.7 g (30% from dimethylformamide dimethyl acetal) of 2-methylaminopyrimidine-4-carboxaldehyde (I-11) as dark brown foam.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951803B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-8a899afe176e40fc8869629906d81d8b |
| Source note | uspto-grants-2011_05 |