HRID552231
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
PROCEDURE
实验过程
The desired compound was prepared according to Method E from (S)-4-((S)-2-Amino-propyl)-6,6-dimethyl-morpholine-3-carboxylic acid (6-chloro-9H-beta-carbolin-8-yl)-amide trifluoroacetate salt and 4-methyl-nicotinic acid in 79% yield. 1H-NMR (300 MHz, DMSO-d6): δ 1.21 (s,3H), 1.22 (d,3H), 1.36 (s,3H), 2.10 (d,1H), 2.40 (m,1H), 2.62 (m,1H), 2.99 (d,1H), 3.22 (m,1H), 3.94 (m,2H), 4.23 (m,1H), 7.26 (d,1H), 7.90 (s,1H), 8.16 (d,1H), 8.23 (s,1H), 8.34-8.46 (m,3H), 9.02 (s,1H), 10.04 (s,1H), 11.27 (s,1H). Retention Time (LC, method: ammonium acetate standard): 2.22 min.
WORKUP
后处理
- custom2.22 min.