tert-butyl N-(4-aminobutyl)carbamate → HCID 67163687, compound

HRID 552365Notes

Reaction equation

HRID 552365 reaction equation
[CH:1]([C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][CH:4]=1)=O.C[Si](C)(C)CCOCN1C=CN=C1C=O.[NH2:28][CH2:29][CH2:30][CH2:31][CH2:32][NH:33][C:34](=[O:40])[O:35][C:36]([CH3:39])([CH3:38])[CH3:37]>>[C:36]([O:35][C:34]([NH:33][CH2:32][CH2:31][CH2:30][CH2:29][NH:28][CH2:1][C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][CH:4]=1)=[O:40])([CH3:39])([CH3:38])[CH3:37]

Participants

4

Reactant 3

HCID 4351tert-butyl N-(4-aminobutyl)carbamateHCID 15294Methyl 4-FormylbenzoateHCID 136002351-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole-2-carbaldehyde

Product 1

HCID 67163687HCID 67163687, compound

Procedure

The same procedure as a series of reactions of Example 1 was carried out, except that methyl 4-formylbenzoate was used in place of 1-({[2-(trimethylsilyl)ethyloxy]methyl}-1H-imidazole-2-carboaldehyde and 1,1-dimethylethyl (4-aminobutyl)carbamate was used in place of {[4-(methyloxy)phenyl]methyl}amine, to obtain the title compound having the following physical properties.

Sources & evidence

ORD record
ord-f880780fe64749f88891648a65e0a85a
Source dataset
uspto-grants-2011_05
Patent number
US07951816B2

Reaction notes

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