反应详情

A solution of 4-nitrobenzenesulfonyl chloride (500 mg, 2.35 mmol), 2-diethylaminoethylamine (300 mg, 0.363 mL, 2.59 mmol) and triethylamine (262 mg, 0.359 mL, 2.59 mmol) in CH2Cl2 (7 mL) was stirred at room temperature for 18 hours. The mixture is then diluted with dichloromethane, and washed with brine. The organic layers is dried (MgSO4) and the solvent is removed under reduced pressure to yield the title compound, which is used as such for the next step.

1. washwashed with brine
2. dry with materialThe organic layers is dried (MgSO4)
3. customthe solvent is removed under reduced pressure