Methyl triflate → HCID 73446474, compound

HRID 552397Notes

Reaction equation

HRID 552397 reaction equation
[F:1][C:2]([F:9])([F:8])[S:3]([O:6]C)(=[O:5])=[O:4].[CH2:10]([O:17][N:18]=[C:19]([C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>C(OCC)C>[F:1][C:2]([F:9])([F:8])[S:3]([O-:6])(=[O:5])=[O:4].[CH2:10]([O:17][N:18]=[C:19]([C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][N+:21]=1[CH3:2])[C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1

Participants

4

Reactant 2

HCID 9526Methyl triflateHCID 72741676HCID 72741676, compound

Product 1

HCID 73446474HCID 73446474, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

17.4 ml (120 mmol) of methyl trifluoromethanesulfonate are added dropwise at 0° C. to a suspension of 35 g (120 mmol) of phenyl(pyridin-2-yl)methanone O-benzyloxime in 200 ml of diethyl ether, and the mixture is stirred at room temperature for 3 h.

Sources & evidence

ORD record
ord-e86884a91168423b9f603378842eeea7
Source dataset
uspto-grants-2011_05
Patent number
US07951821B2

Reaction notes

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