HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 4-Bromo-6-methylpyridine-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 6-methyl-4-nitropicolinic acid | HCID 11275391 | — |
| Product | 4-Bromo-6-methylpyridine-2-carboxylic acid | HCID 53485295 | — |
Reaction Steps
A solution of 3.6 g (19.6 mmol) of 6-Methyl-4-nitro-pyridine-2-carboxylic acid in 40 ml of 48% hydrobromic acid was heated at 100° C. overnight and then allowed to cool to room temperature. The solution was then evaporated to dryness in vaccuo. The crude material (10.5 g) containing inorganic salts was directly used in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951824B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-7534d19fc07f4379a371d23045f25060 |
| Source note | uspto-grants-2011_05 |