2-Amino-4-methylthiazole → HCID 86614582, compound

HRID 552496Notes

Reaction equation

HRID 552496 reaction equation
C(O[C:4]([C:6]1[C:11]([CH3:12])=[C:10]([Br:13])[CH:9]=[C:8]([CH3:14])[N:7]=1)=[O:5])C.[NH2:15][C:16]1[S:17][CH:18]=[C:19]([CH3:21])[N:20]=1>>[CH3:21][C:19]1[N:20]=[C:16]([NH:15][C:4]([C:6]2[C:11]([CH3:12])=[C:10]([Br:13])[CH:9]=[C:8]([CH3:14])[N:7]=2)=[O:5])[S:17][CH:18]=1

Participants

3

Reactant 2

HCID 741432-Amino-4-methylthiazoleHCID 67163821HCID 67163821, compound

Product 1

HCID 86614582HCID 86614582, compound

Procedure

The title compound, white solid, MS (ISP): m/e=326.1, 328.0 (M+H)+, was prepared from 4-Bromo-3,6-dimethyl-pyridine-2-carboxylic acid ethyl ester and 2-Amino-4-methylthiazole in accordance with the general method of example 1, step 5.

Sources & evidence

ORD record
ord-51c2af93d66c4259b9b917223d5003cf
Source dataset
uspto-grants-2011_05
Patent number
US07951824B2

Reaction notes

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