huagongshe.com
HRID552505

反应详情

EQUATION

反应方程式

HRID 552505 的结构方程式

REACTANTS

反应物

2
结构：Fc1cnc(Cl)cc1I
HCID24820495

2-Chloro-5-fluoro-4-iodopyridine

C5H2ClFIN

结构：Cc1cc(B2OC(C)(C)C(C)(C)O2)cc(C(=O)Nc2nc(C)cs2)n1
HCID49760412

6-Methyl-N-(4-methyl-1,3-thiazol-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carboxamide

C17H22BN3O3S

PRODUCTS

生成物

1
结构：Cc1cc(-c2cc(Cl)ncc2F)cc(C(=O)Nc2nc(C)cs2)n1
HCID24820892

未命名化合物

PROCEDURE

实验过程

The title compound, was prepared from 6-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine-2-carboxylic acid (4-methyl-thiazol-2-yl)-amide in accordance with the general method of example 131, step 2 using 2-Chloro-5-fluoro-4-iodopyridine instead of 3-Trifluoromethyl-5-bromopyridine to yield the final compound as a off-white solid, MS (ISP): m/e=363.2, 365.1 (M+H)+.