2-Chloro-5-fluoro-4-iodopyridine → 2'-Chloro-5'-fluoro-6-methyl-[4,4']bipyridinyl-2-carboxylic acid (4-methyl-thiazol-2-yl)-amide

Beteiligte Stoffe

Reaktionsschritte

The title compound, was prepared from 6-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine-2-carboxylic acid (4-methyl-thiazol-2-yl)-amide in accordance with the general method of example 131, step 2 using 2-Chloro-5-fluoro-4-iodopyridine instead of 3-Trifluoromethyl-5-bromopyridine to yield the final compound as a off-white solid, MS (ISP): m/e=363.2, 365.1 (M+H)+.

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