HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-5-methylpyridine → 5,6'-Dimethyl-[3,4']bipyridinyl-2'-carboxylic acid (2-chloro-pyridin-4-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-5-methylpyridine | HCID 817713 | — |
| Reactant | N-(2-Chloropyridin-4-yl)-6-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carboxamide | HCID 49760409 | — |
| Product | 5,6'-Dimethyl-[3,4']bipyridinyl-2'-carboxylic acid (2-chloro-pyridin-4-yl)-amide | HCID 86614587 | — |
Reaction Steps
The title compound, was prepared from 6-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine-2-carboxylic acid (2-chloro-pyridin-4-yl)-amide in accordance with the general method of example 131, step 2 using 3-Bromo-5-methylpyridine instead of 3-Trifluoromethyl-5-bromopyridine to yield the final compound as a white solid, MS (ISP): m/e=339.1, 341.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951824B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-0b79850825a643418be8b54e0960e754 |
| Source note | uspto-grants-2011_05 |