HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3,5-Difluorophenyl)boronic acid → 4-(3,5-Difluorophenyl)-6-methyl-pyridine-2-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3,5-Difluorophenyl)boronic acid | HCID 2734338 | — |
| Reactant | Ethyl 4-bromo-6-methylpicolinate | HCID 25208981 | — |
| Product | 4-(3,5-Difluorophenyl)-6-methyl-pyridine-2-carboxylic acid ethyl ester | HCID 67163999 | — |
Reaction Steps
The title compound, was prepared from 4-Bromo-6-methyl-pyridine-2-carboxylic acid ethyl ester (example 1, step 4) in accordance with the general method of example 1, step 6 using 3,5-Difluorophenylboronic acid instead of 3-Fluorophenylboronic acid to yield the final compound as a white crystalline solid, MS (ISP): m/e=278.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951824B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-812105f6cd444623a55950091e1ca7e0 |
| Source note | uspto-grants-2011_05 |