HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminopyridine-2-carbonitrile → 4-(3,5-Difluorophenyl)-6-methyl-pyridine-2-carboxylic acid (2-cyano-pyridin-4-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminopyridine-2-carbonitrile | HCID 23131454 | — |
| Reactant | 4-(3,5-Difluorophenyl)-6-methyl-pyridine-2-carboxylic acid ethyl ester | HCID 67163999 | — |
| Product | 4-(3,5-Difluorophenyl)-6-methyl-pyridine-2-carboxylic acid (2-cyano-pyridin-4-yl)-amide | HCID 67164225 | — |
Reaction Steps
The title compound, was prepared from 4-(3,5-Difluorophenyl)-6-methyl-pyridine-2-carboxylic acid ethyl ester in accordance with the general method of example 26, step 6 using 4-Amino-pyridine-2-carbonitrile instead of 3-chloroaniline to yield the final compound as a white crystalline, MS (ISP): m/e=351.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951824B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-6fb7de74acad4b828cead560ce561c59 |
| Source note | uspto-grants-2011_05 |