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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 552530Generated: October 31, 2026

ethyl 2-(3-amino-1H-pyrazol-1-yl)acetate → (3-{[4-(3,5-Difluorophenyl)-6-methyl-pyridine-2-carbonyl]-amino}-pyrazol-1-yl)-acetic acid ethyl ester

https://huagongshe.com/reaction/552530

Reaction equation

Participants

RoleNameHCIDCharge
Reactantethyl 2-(3-amino-1H-pyrazol-1-yl)acetateHCID 5200378—
Reactant4-(3,5-Difluorophenyl)-6-methyl-pyridine-2-carboxylic acid ethyl esterHCID 67163999—
Product(3-{[4-(3,5-Difluorophenyl)-6-methyl-pyridine-2-carbonyl]-amino}-pyrazol-1-yl)-acetic acid ethyl esterHCID 24820977—

Reaction Steps

The title compound, was prepared from 4-(3,5-Difluorophenyl)-6-methyl-pyridine-2-carboxylic acid ethyl ester in accordance with the general method of example 26, step 6 using Ethyl (3-Amino-1-pyrazolyl)acetate instead of 3-chloroaniline to yield the final compound as a white crystalline, MS (ISP): m/e=401.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07951824B2
Source datasetuspto-grants-2011_05
ORD IDord-4ab2db359ba041b287a1932c927f02a1
Source noteuspto-grants-2011_05