HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Fluoro-6'-methyl-[3,4']bipyridinyl-2'-carboxylic acid ethyl ester → 5-Fluoro-6'-methyl-[3,4']bipyridinyl-2'-carboxylic acid (4-cyclopentyl-thiazol-2-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Fluoro-6'-methyl-[3,4']bipyridinyl-2'-carboxylic acid ethyl ester | HCID 67164770 | — |
| Reactant | 4-Cyclopentyl-1,3-thiazol-2-amine hydrochloride | HCID 131728931 | — |
| Product | 5-Fluoro-6'-methyl-[3,4']bipyridinyl-2'-carboxylic acid (4-cyclopentyl-thiazol-2-yl)-amide | HCID 24820907 | — |
Reaction Steps
The title compound, was prepared from 5-Fluoro-6′-methyl-[3,4′]bipyridinyl-2′-carboxylic acid ethyl ester in accordance with the general method of example 26, step 6 using 4-Cyclopentyl-thiazol-2-ylamine, hydrochloride instead of 3-chloroaniline to yield the final compound as a white solid, MS (ISP): m/e=383 [M]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951824B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-64779f3a773a43f19805d7f43d6dc469 |
| Source note | uspto-grants-2011_05 |