HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoroaniline → 5-Fluoro-6'-methyl-[3,4']bipyridinyl-2'-carboxylic acid (4-fluoro-phenyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoroaniline | HCID 9731 | — |
| Reactant | 5-Fluoro-6'-methyl-[3,4']bipyridinyl-2'-carboxylic acid ethyl ester | HCID 67164770 | — |
| Product | 5-Fluoro-6'-methyl-[3,4']bipyridinyl-2'-carboxylic acid (4-fluoro-phenyl)-amide | HCID 67163974 | — |
Reaction Steps
The title compound, was prepared from 5-Fluoro-6′-methyl-[3,4′]bipyridinyl-2′-carboxylic acid ethyl ester in accordance with the general method of example 26, step 6 using 4-Fluoroaniline instead of 3-chloroaniline to yield the final compound as a gray solid, MS (ISP): m/e=324.9, 326.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951824B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-fdf49f94fb6b4e46bdf0f2d642ee0cf6 |
| Source note | uspto-grants-2011_05 |