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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 552540Generated: October 30, 2026

2-Chloropyridine-4-boronic acid → 2'-Chloro-6-methyl-[4,4']bipyridinyl-2-carboxylic acid ethyl ester

https://huagongshe.com/reaction/552540

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloropyridine-4-boronic acidHCID 5151595—
ReactantEthyl 4-bromo-6-methylpicolinateHCID 25208981—
Product2'-Chloro-6-methyl-[4,4']bipyridinyl-2-carboxylic acid ethyl esterHCID 86614590—

Reaction Steps

The title compound, was prepared from 4-Bromo-6-methyl-pyridine-2-carboxylic acid ethyl ester (example 1, step 4) and 2-Chloropyridine-4-boronic acid in accordance with the general method of example 1, step 6 to yield the final compound as a light yellow oil, MS (ISP): m/e=277.1 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07951824B2
Source datasetuspto-grants-2011_05
ORD IDord-f711cc18762345cba6efb52829fab4fb
Source noteuspto-grants-2011_05