HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 3-Amino-1H-indazole-6-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | 1,4-Benzenedicarbonitrile, 2-fluoro- | HCID 121194 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Amino-1H-indazole-6-carbonitrile | HCID 22615272 | — |
Reaction Steps
To a solution of 2-fluoroterephthalonitrile (500 mg) and Et3N (572 μl) in EtOH (20 ml) was added hydrazine (monohydrate), followed by reaction at 60° C. for 16 hours, and concentrated. The residue was washed with diethyl ether to obtain 3-amino-1H-indazole-6-carbonitrile (488 mg) as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951825B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-e337d8c16ae746e7a59bda4d9b990d1e |
| Source note | uspto-grants-2011_05 |