反应详情

Under the conditions of example 5A, 6.2 g of N-(3-iodophenyl)-1,1,1-trifluoromethanesulfonamide is reacted with 2.07 g of trimethylsilylacetylene, worked up, and the crude product is chromatographed on silica gel with hexane/0-25% ethyl acetate. 2.72 g of N-[3-(2-trimethylsilylethinyl)-phenyl]-1,1,1-trifluoromethanesulfonamide is obtained as yellow oil.

1. customthe crude product is chromatographed on silica gel with hexane/0-25% ethyl acetate