Piperidine → 1-[2-Methyl-2-(4-nitro-imidazol-1-yl)-propyl]-piperidine

HRID 553095Notes

Reaction equation

HRID 553095 reaction equation
[CH3:1][C:2]([N:6]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[N:8]=[CH:7]1)([CH3:5])[CH:3]=O.[NH:14]1[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1>>[CH3:1][C:2]([N:6]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[N:8]=[CH:7]1)([CH3:5])[CH2:3][N:14]1[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1

Participants

3

Reactant 2

HCID 8082PiperidineHCID 866008092-Methyl-2-(4-nitro-imidazol-1-yl)-propionaldehyde

Product 1

HCID 671629661-[2-Methyl-2-(4-nitro-imidazol-1-yl)-propyl]-piperidine

Procedure

2-Methyl-2-(4-nitro-imidazol-1-yl)-propionaldehyde was reacted with piperidine to provide the title compound: C13 NMR (100 MHz, CDCl3) 23.8, 25.6, 26.6, 57.0, 60.9, 69.2, 118.3, 134.4; MS m/z 253.3 (M+1).

Sources & evidence

ORD record
ord-9b920b2bbe974400969bdd6709be4cb5
Source dataset
uspto-grants-2011_05
Patent number
US07951958B2

Reaction notes

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