HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → P 276-00
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (+)-trans-2-(2-Chloro-phenyl)-8-(2-hydroxymethyl-1-methyl-pyrrolidin-3-yl)-5,7-dimethoxy-chromen-4-one | HCID 59318486 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | P 276-00 | HCID 23643975 | — |
Reaction Steps
(+)-trans-2-(2-Chlorophenyl)-8-(2-hydroxymethyl-1-methyl-pyrrolidin-3-yl)-5,7-dimethoxy-chromen-4-one (0.2 g, 0.48 mmol) was suspended in methanol (2 mL) and ethereal HCl (5 mL) was added. The suspension was stirred to get a clear solution. The solution was concentrated under reduced pressure to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951961B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-9c160ae55da34d50b200614afaff8436 |
| Source note | uspto-grants-2011_05 |