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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 553323Generated: October 25, 2026

(S)-1-methoxybutan-2-amine hydrochloride → (1-Methoxymethyl-propyl)-{3-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-benzyl}-amine

https://huagongshe.com/reaction/553323

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-1-methoxybutan-2-amine hydrochlorideHCID 46941497—
ReactantHCID 86618325HCID 86618325—
Product(1-Methoxymethyl-propyl)-{3-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-benzyl}-amineHCID 67165222—

Reaction Steps

The sub-titled compound was prepared from (S)-1-methoxymethyl-propylamine hydrochloride (0.36 g) and 3-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-benzaldehyde (Example 50, step a, 0.5 g) using the method of Example 75, step b. Yield 0.6 g.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07951954B2
Source datasetuspto-grants-2011_05
ORD IDord-87b9dad2a7c44b62a0349d7333cb740c
Source noteuspto-grants-2011_05