HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanemethanamine → HCID 57434473, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanemethanamine | HCID 75646 | — |
| Reactant | 5-(1,1-Dimethylethyl) 6,7-dihydroisoxazolo[4,5-c]pyridine-3,5(4H)-dicarboxylate | HCID 57618622 | — |
| Product | HCID 57434473 | HCID 57434473 | 78% |
Reaction Steps
In a manner similar to general method 1, 280 mg (1.0 mmol) of 6,7-dihydro-4H-isoxazolo[4,5-c]pyridine-3,5-dicarboxylic acid 5-tert-butyl ester were reacted with 90 μL of cyclopropylmethylamine to yield 260 mg (78% of theoretical) of 3-(cyclopropylmethyl-carbamoyl)-6,7-dihydro-4H-isoxazolo[4,5-c]pyridine-5-carboxylic acid tert-butyl ester, which were obtained in the form of a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08048879B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-8cff61c06ad540ab90ca30614e438f38 |
| Source note | uspto-grants-2011_11 |