反应详情

2-Fluorobenzaldehyde (15.8 ml) was dissolved in ethanol (100 ml) and to the stirred solution was added malonitrile (9.9 g). The solution was heated to reflux, the heating discontinued and piperidine (4 drops) was added. Once the vigorous reaction had diminished, the solution was heated for 15 minutes and then chilled. Crystals of product were filtered off and washed with ethanol, m.p. 122° C.

1. temperatureThe solution was heated
2. temperatureto reflux
3. customOnce the vigorous reaction
4. temperaturethe solution was heated for 15 minutes
5. temperaturechilled
6. filtrationCrystals of product were filtered off
7. washwashed with ethanol, m.p. 122° C.