Hydrochloric Acid → Methyl 2-amino-3-(3-hydroxyphenyl)propanoate

HRID 553817Notes

Reaction equation

HRID 553817 reaction equation
[CH:1]1[CH:6]=[C:5]([OH:7])[CH:4]=[C:3]([CH2:8][CH:9]([NH2:13])[C:10]([OH:12])=[O:11])[CH:2]=1.Cl.[CH3:15]O>>[CH3:15][O:11][C:10](=[O:12])[CH:9]([NH2:13])[CH2:8][C:3]1[CH:2]=[CH:1][CH:6]=[C:5]([OH:7])[CH:4]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 130523-Tyrosine, DL-

Product 1

HCID 22386100Methyl 2-amino-3-(3-hydroxyphenyl)propanoate

Procedure

DL-m-Tyrosine (1 g) was stirred in a 3M solution of HCl in MeOH (10 ml) for 2 h at RT The solvent was removed and HV drying afforded 1.43 g of the desired compound.

Workup

  1. customwas removed
  2. customHV drying

Sources & evidence

ORD record
ord-e4efb3f233254d498547e13133f49e9c
Source dataset
uspto-grants-2011_11
Patent number
US08048881B2

Reaction notes

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