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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 553874Generated: October 31, 2026

HCID 69076198, compound → HCID 69077797, compound

https://huagongshe.com/reaction/553874

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69076198HCID 69076198—
ReactantHCID 178418361HCID 178418361—
CatalystPlatinum oxide (PtO)HCID 82844—
SolventMethanolHCID 887—
ProductHCID 69077797HCID 6907779782.1%

Reaction Steps

Platinum oxide (10 mg) was added to a solution of (5R*,8aS*)-5-(4-fluorophenyl)-6,7,8,8a-tetrahydro-5H-indolizin-3-one (105 mg) in methanol (5 mL), and the reaction solution was stirred in a hydrogen stream at room temperature for three hours. The reaction solution was filtered through celite, and the filtrate was concentrated under reduced pressure to obtain 87 mg of the title compound. The property value of the compound is as follows.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08048878B2
Source datasetuspto-grants-2011_11
ORD IDord-611041b2f3184802b18c1107e970abae
Source noteuspto-grants-2011_11