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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 553975Generated: October 31, 2026

HCID 67463031, compound → HCID 67460105, compound

https://huagongshe.com/reaction/553975

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67463031HCID 67463031—
ReactantHCID 178418361HCID 178418361—
CatalystPlatinum oxide (PtO)HCID 82844—
SolventMethanolHCID 887—
ProductHCID 67460105HCID 6746010599.6%

Reaction Steps

Platinum oxide (25 mg) was added to a solution of (3S,8aR)-3-(2,4,6-trifluorophenyl)-2,3,6,8a-tetrahydro-1H-indolizin-5-one (548 mg) in methanol (5 mL), and the reaction solution was stirred in a hydrogen atmosphere at 1 atm at room temperature for one hour. The reaction solution was filtered through celite, and the filtrate was concentrated under reduced pressure to obtain 550 mg of the title compound. The property value of the compound is as follows.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08048878B2
Source datasetuspto-grants-2011_11
ORD IDord-f0b49e79cd9541f6a0dae8b893f9b966
Source noteuspto-grants-2011_11