HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzaldehyde → (S)-1-Benzyl-5-carboxy-2-pyrrolidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-1-(2,2-dimethylpropyl)-5-oxoprolinamide | HCID 67460075 | — |
| Product | (S)-1-Benzyl-5-carboxy-2-pyrrolidinone | HCID 10900113 | — |
Reaction Steps
5-oxo-1-(phenylmethyl)proline was prepared in an analogous manner to that described above for the synthesis of 1-(2,2-dimethylpropyl)-5-oxoproline (example 100) but using benzaldehyde in the place of trimethylacetaldehyde.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08048907B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-38a887ced9484ef6b6f8654471eaf5ea |
| Source note | uspto-grants-2011_11 |