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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 554141Generated: October 28, 2026

2,4-Dichlorobenzylamine → N-[(2,4-dichlorophenyl)methyl]-5-oxo-1-(3-pyridinylmethyl)prolinamide

https://huagongshe.com/reaction/554141

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DichlorobenzylamineHCID 1485—
ReactantN-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-5-oxo-1-(3-pyridinylmethyl)prolinamideHCID 67459890—
ProductN-[(2,4-dichlorophenyl)methyl]-5-oxo-1-(3-pyridinylmethyl)prolinamideHCID 67462337—

Reaction Steps

N-[(2,4-dichlorophenyl)methyl]-5-oxo-1-(3-pyridinylmethyl)prolinamide was prepared in a manner analogous to that described above for the synthesis of N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-5-oxo-1-(3-pyridinylmethyl)prolinamide (E120) but using [(2,4-dichlorophenyl)methyl]amine in the place of {[2-chloro-3-(trifluoromethyl)phenyl]methyl}amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08048907B2
Source datasetuspto-grants-2011_11
ORD IDord-d77667629eef4e26a1db661d1976acec
Source noteuspto-grants-2011_11